منابع مشابه
Coexpression of Myosin Heavy Chain 2b with Myosin Heavy Chain 1- Fact or Artefact
In skeletal muscle, pure fibres expressing one myosin heavy chain (MyHC) isoform, and intermediate fibres, expressing two and exceptionally three MyHCs have been described. When skeletal muscle adapts its fibre type profile to changed functional demands MyHC isoform transformation follows the pathway: MyHC-1 ↔ MyHC-2a ↔ MyHC-2x/d ↔ MyHC-2b. Therefore, in hybrid fibres only successive isoforms f...
متن کاملPurification of Myosin Heavy Chain Isoforms by Electroendos- motic Preparative Gel Electrophoresis: Characterization of Em- bryonic Slow Myosin Heavy Chain
Myosin is a hexapolypeptide constituted by four light and two heavy chains the isoforms of which segregate differently in specific stages of animal development and in different fiber types in adulthood. In mammals the Myosin Heavy Chains (MHC) are polypeptides with a molecular mass of about 200 KDa which isoforms can be identified by SDS PAGE and/or immunochemistry. A method for the purificatio...
متن کاملThree-dimensional compartmentalization of myosin heavy chain and myosin light chain isoforms in dog thyroarytenoid muscle.
The thyroarytenoid muscle, a vocal fold adductor, has important roles in airway protection (e.g., prevention of aspiration) and phonation. Isoform expression of myosin heavy chain (MHC), a major determinant of muscle-shortening velocity, has been reported to be heterogeneous in this muscle in several mammals, differing markedly between the medial and lateral divisions. The objective was to dete...
متن کاملRegional Myosin heavy chain distribution in selected paraspinal muscles.
STUDY DESIGN Cross-sectional study with repeated measures design. OBJECTIVE To compare the myosin heavy-chain isoform distribution within and between paraspinal muscles and to test the theory that fiber-type gradients exist as a function of paraspinal muscle depth. SUMMARY OF BACKGROUND DATA There is still uncertainty regarding the fiber-type distributions within different paraspinal muscle...
متن کاملSpatial distribution of myosin heavy-chain isoforms in mouse masseter.
There is a paucity of information regarding the anatomy and muscle fiber phenotype of the masseter. The objective of this study was to characterize the distribution of each myosin heavy-chain (MyHC) isoform within different anatomical regions of male and female mouse masseters. Masseters from male and female CD-1 mice (2-4 months old) were examined for description of the anatomical partitioning...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/37527